TIGAR antibody (AA 1-269) (Fluoro488)

Catalog No. ABIN8047635

The Rabbit Polyclonal anti-TIGAR antibody is suitable to detect TIGAR in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for TIGAR antibody (AA 1-269) (Fluoro488) (ABIN8047635)

Target: TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIGAR antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-TIGAR Antibody (Fluoro488)

Binding Specificity: AA 1-269

Purpose: Anti-TIGAR Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse TIGAR shares 72.8% amino acid (aa) sequence identity with human TIGAR.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse TIGAR recombinant protein (Position: M1-H269). Mouse TIGAR shares 72.8% amino acid (aa) sequence identity with human TIGAR.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TIGAR

Target: TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))

Alternative Name: TIGAR

Background:

Background: Enables fructose-2,6-bisphosphate 2-phosphatase activity. Involved in positive regulation of pentose-phosphate shunt and response to ischemia. Acts upstream of or within several processes, including fructose 2,6-bisphosphate metabolic process, negative regulation of catabolic process, and positive regulation of cardiac muscle cell apoptotic process. Located in mitochondrion. Is expressed in several structures, including brain, heart, immune system, and liver. Orthologous to human TIGAR (TP53 induced glycolysis regulatory phosphatase).

Gene Full Name: Trp53 induced glycolysis regulatory phosphatase

Gene ID: 319801

UniProt: Q8BZA9

Pathways: Warburg Effect