TRIOBP antibody (AA 1079-2365) (FITC)

Catalog No. ABIN8049609

The Rabbit Polyclonal anti-TRIOBP antibody is suitable to detect TRIOBP in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for TRIOBP antibody (AA 1079-2365) (FITC) (ABIN8049609)

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIOBP antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-TRIOBP Antibody (FITC)

Binding Specificity: AA 1079-2365

Purpose: Anti-TRIOBP Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TRIOBP shares 78.1% amino acid (aa) sequence identity with mouse TRIOBP.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRIOBP recombinant protein (Position: H1079-E2365). Human TRIOBP shares 78.1% amino acid (aa) sequence identity with mouse TRIOBP.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRIOBP

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Alternative Name: TRIOBP

Background:

Background: This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).

Gene Full Name: TRIO and F-actin binding protein

Gene ID: 11078

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization