TRIOBP antibody (AA 1079-2365)

Catalog No. ABIN8049614

This Rabbit Polyclonal antibody specifically detects TRIOBP in WB, IHC, ELISA, FACS, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TRIOBP antibody (AA 1079-2365) (ABIN8049614)

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIOBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Grade: Carrier-free

Product Details anti-TRIOBP Antibody

Binding Specificity: AA 1079-2365

Purpose: Anti-TRIOBP Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TRIOBP shares 78.1% amino acid (aa) sequence identity with mouse TRIOBP.

Characteristics: Anti-TRIOBP Antibody. Tested in WB, IHC, IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRIOBP recombinant protein (Position: H1079-E2365). Human TRIOBP shares 78.1% amino acid (aa) sequence identity with mouse TRIOBP.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TRIOBP

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Alternative Name: TRIOBP

Background:

Background: This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).

Gene Full Name: TRIO and F-actin binding protein

Molecular Weight: 75 kDa

Gene ID: 11078

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization