TYRO3 antibody (AA 48-882) (Fluoro488)

Catalog No. ABIN8051767

The Fluoro488-conjugated Rabbit Polyclonal anti-TYRO3 antibody (ABIN8051767) specifically detects TYRO3 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TYRO3 antibody (AA 48-882) (Fluoro488) (ABIN8051767)

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYRO3 antibody is conjugated to Fluoro488

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TYRO3 Antibody (Fluoro488)

Binding Specificity: AA 48-882

Purpose: Anti-TYRO3 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TYRO3 shares 89.6% amino acid (aa) sequence identity with both mouse,rat TYRO3.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TYRO3 recombinant protein (Position: A48-Q882). Human TYRO3 shares 89.6% amino acid (aa) sequence identity with both mouse and rat TYRO3.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human ELISA, 0.1-0.5 μg/mL

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TYRO3

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Alternative Name: TYRO3

Background:

Background: The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.

Gene Full Name: TYRO3 protein tyrosine kinase

Gene ID: 7301

UniProt: Q06418

Pathways: RTK Signaling