UBXN8 antibody (AA 149-270) (Fluoro647)

Catalog No. ABIN8052573

The Rabbit Polyclonal anti-UBXN8 antibody is suitable to detect UBXN8 in samples from Human. It has been validated for FACS.

Quick Overview for UBXN8 antibody (AA 149-270) (Fluoro647) (ABIN8052573)

Target: UBXN8 (UBX Domain Protein 8 (UBXN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBXN8 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-UBXN8 Antibody (Fluoro647)

Binding Specificity: AA 149-270

Purpose: Anti-UBXN8 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human UBXN8 recombinant protein (Position: N149-N270).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for UBXN8

Target: UBXN8 (UBX Domain Protein 8 (UBXN8))

Alternative Name: UBXN8

Background:

Background: p97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: UBX domain protein 8

Gene ID: 7993

UniProt: O00124

Pathways: SARS-CoV-2 Protein Interactome