UBXN8 antibody (AA 149-270)

Catalog No. ABIN8052574

The Rabbit Polyclonal anti-UBXN8 antibody (ABIN8052574) specifically detects UBXN8 in ELISA, WB, FACS and IHC. The antibody is reactive with Human samples.

Quick Overview for UBXN8 antibody (AA 149-270) (ABIN8052574)

Target: UBXN8 (UBX Domain Protein 8 (UBXN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBXN8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-UBXN8 Antibody

Binding Specificity: AA 149-270

Purpose: Anti-UBXN8 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-UBXN8 Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human UBXN8 recombinant protein (Position: N149-N270).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBXN8

Target: UBXN8 (UBX Domain Protein 8 (UBXN8))

Alternative Name: UBXN8

Background:

Background: p97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: UBX domain protein 8

Molecular Weight: 36 kDa

Gene ID: 7993

UniProt: O00124

Pathways: SARS-CoV-2 Protein Interactome