Uroplakin 1B antibody (AA 107-216) (Fluoro488)

Catalog No. ABIN8052930

The Rabbit Polyclonal anti-Uroplakin 1B antibody is suitable to detect Uroplakin 1B in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Uroplakin 1B antibody (AA 107-216) (Fluoro488) (ABIN8052930)

Target: Uroplakin 1B (UPK1B)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 1B antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Uroplakin 1B Antibody (Fluoro488)

Binding Specificity: AA 107-216

Purpose: Anti-Uroplakin Ib/UPIb Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Uroplakin Ib/UPIb recombinant protein (Position: I107-Q216).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: UPK1B

Background:

Background: Uroplakin 1B, also known as UPK1B, is a protein which in humans is encoded by the UPK1B gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.

Gene Full Name: uroplakin 1B

Gene ID: 7348

UniProt: O75841