WIPF1 antibody (C-Term) (Biotin)

Catalog No. ABIN8053918

The Biotin-conjugated Rabbit Polyclonal anti-WIPF1 antibody (ABIN8053918) specifically detects WIPF1 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for WIPF1 antibody (C-Term) (Biotin) (ABIN8053918)

Target: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPF1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-WIPF1 Antibody (Biotin)

Binding Specificity: C-Term

Purpose: Anti-WIPF1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human WIPF1, which shares 95% amino acid (aa) sequence identity with mouse and rat WIPF1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for WIPF1

Target: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Alternative Name: WIPF1

Background:

Background: WAS/WASL-interacting protein (WIP) is a protein that in humans is encoded by the WIPF1 gene. This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.

Gene Full Name: WAS/WASL interacting protein family member 1

Gene ID: 7456

UniProt: O43516

Pathways: RTK Signaling