WHSC1 antibody (AA 2-478) (Fluoro594)

Catalog No. ABIN8054462

This Rabbit Polyclonal antibody specifically detects WHSC1 in FACS. It exhibits reactivity toward Human and Monkey.

Quick Overview for WHSC1 antibody (AA 2-478) (Fluoro594) (ABIN8054462)

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WHSC1 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-WHSC1 Antibody (Fluoro594)

Binding Specificity: AA 2-478

Purpose: Anti-WHSC1/NSD2 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WHSC1/NSD2 recombinant protein (Position: E2-A478).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Alternative Name: NSD2

Background:

Background: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4,14)(p16.3,q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Gene Full Name: nuclear receptor binding SET domain protein 2

Gene ID: 7468

UniProt: O96028

Pathways: SARS-CoV-2 Protein Interactome