CARM1 antibody (pSer228) (Cy5.5)
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- Target See all CARM1 Antibodies
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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Binding Specificity
- pSer228
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CARM1 antibody is conjugated to Cy5.5
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human CARM1 around the phosphorylation site of Ser228
- Isotype
- IgG
- Top Product
- Discover our top product CARM1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
- Alternative Name
- CARM1 (CARM1 Products)
- Synonyms
- NV18905 antibody, prmt4 antibody, PRMT4 antibody, Prmt4 antibody, si:dkey-204f11.63 antibody, zgc:100805 antibody, coactivator associated arginine methyltransferase 1 antibody, coactivator associated arginine methyltransferase 1 L homeolog antibody, coactivator-associated arginine methyltransferase 1 antibody, histone-arginine methyltransferase CARM1 antibody, CARM1 antibody, carm1.L antibody, Carm1 antibody, carm1 antibody, LOC100352221 antibody
- Background
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Synonyms: CARM1_HUMAN, Coactivator associated arginine methyltransferase 1, Coactivator-associated arginine methyltransferase 1, Histone arginine methyltransferase CARM 1, Histone arginine methyltransferase CARM1, Histone-arginine methyltransferase CARM1, PRMT 4, Protein arginine methyltransferase, Protein arginine N methyltransferase 4, Protein arginine N-methyltransferase 4.
Background: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
- Gene ID
- 10498
- UniProt
- Q86X55
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
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