Chaperonin GroEL (GroEL) (AA 401-495) antibody (HRP)

Catalog No. ABIN758570

Product Details

Target: Chaperonin GroEL (GroEL)

Binding Specificity: AA 401-495

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSP58/Cornulin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Chaperonin GroEL (GroEL)

Alternative Name: HSP58 (GroEL Products)

Synonyms: CPN60 antibody, GROEL antibody, HLD4 antibody, HSP-60 antibody, HSP60 antibody, HSP65 antibody, HuCHA60 antibody, SPG13 antibody, cpn60_1 antibody, heat shock protein family D (Hsp60) member 1 antibody, chaperonin GroEL antibody, chaperonin antibody, GroEL antibody, groEL antibody, 60 KDA CHAPERONIN 2 GROEL2 (PROTEIN CPN60-2) (GROEL PROTEIN 2) (65 KDA ANTIGEN) (HEAT SHOCK PROTEIN 65) (CELL WALL PROTEIN A) (ANTIGEN A) antibody, Cpn60; groEL antibody, molecular chaperone GroEL antibody, HSPD1 antibody, groEL1 antibody, groEL antibody, groEL2 antibody, APH_RS01055 antibody

Background:

Synonyms: HSP 58, HSP-58, PDRC1, 53 kDa putative calcium binding protein, 53 kDa squamous epithelial induced stress protein, 58 kDa heat shock protein, C1orf10, Chromosome 1 open reading frame 10, CRNN, DRC1, SEP53, Squamous epithelial heat shock protein 53, Tumor related protein, CRNN_HUMAN, HSP58/Cornulin.

Background: This gene encodes a member of the "fused gene" family of proteins, which contain N terminus EF hand domains and multiple tandem peptide repeats. The encoded protein contains two EF hand Ca2+ binding domains in its N terminus and two glutamine and threonine rich 60 amino acid repeats in its C terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.

Gene ID: 49860