CHRNA6 antibody (Middle Region)

Catalog No. ABIN8096958

The Rabbit Polyclonal anti-CHRNA6 antibody (ABIN8096958) specifically detects CHRNA6 in WB. The antibody is reactive with Human samples.

Quick Overview for CHRNA6 antibody (Middle Region) (ABIN8096958)

Target: CHRNA6 (Cholinergic Receptor, Nicotinic, alpha 6 (CHRNA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRNA6 Antibody

Binding Specificity: Middle Region

Purpose: CHRNA6 Antibody - middle region

Sequence: KFGSWTYDKA EIDLLIIGSK VDMNDFWENS EWEIIDASGY KHDIKYNCCE

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ACHA6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73928-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNA6

Target: CHRNA6 (Cholinergic Receptor, Nicotinic, alpha 6 (CHRNA6))

Alternative Name: CHRNA6

Background:

Background Information: This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.

Gene Name: cholinergic receptor nicotinic alpha 6 subunit

Alternative Symbols: CHNRA6

Protein Name: neuronal acetylcholine receptor subunit alpha-6

Molecular Weight: 54kDa

Gene ID: 8973

NCBI Accession: NP_004189

UniProt: Q15825