GABRB2 antibody (N-Term)

Catalog No. ABIN8101270

This Rabbit Polyclonal antibody specifically detects GABRB2 in WB. It exhibits reactivity toward Human.

Quick Overview for GABRB2 antibody (N-Term) (ABIN8101270)

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABRB2 Antibody

Binding Specificity: N-Term

Purpose: GABRB2 Antibody - N-terminal region

Sequence: MNIDIASIDM VSEVNMDYTL TMYFQQAWRD KRLSYNVIPL NLTLDNRVAD

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GBRB2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76179-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRB2

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Alternative Name: GABRB2

Background:

Background Information: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.

Gene Name: gamma-aminobutyric acid type A receptor beta2 subunit

Alternative Symbols: DEE92, ICEE2

Protein Name: gamma-aminobutyric acid receptor subunit beta-2

Molecular Weight: 56kDa

Gene ID: 2561

NCBI Accession: NP_068711

UniProt: P47870

Pathways: Sensory Perception of Sound, Synaptic Membrane