MAPK11 antibody (N-Term)

Catalog No. ABIN8105615

The Rabbit Polyclonal anti-MAPK11 antibody is suitable to detect MAPK11 in samples from Human, Mouse, Rat, Cow and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for MAPK11 antibody (N-Term) (ABIN8105615)

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAPK11 Antibody

Binding Specificity: N-Term

Purpose: MAPK11 Antibody - N-terminal region

Sequence: MSGPRAGFYR QELNKTVWEV PQRLQGLRPV GSGAYGSVCS AYDARLRQKV

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 91%

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MK11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56437-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAPK11

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Alternative Name: MAPK11

Background:

Background Information: This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants.

Gene Name: mitogen-activated protein kinase 11

Alternative Symbols: P38B, SAPK2, p38-2, PRKM11, SAPK2B, p38Beta, P38BETA2

Protein Name: mitogen-activated protein kinase 11

Molecular Weight: 40kDa

Gene ID: 5600

NCBI Accession: NP_002742

UniProt: Q15759

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins