CASC5 antibody (AA 2251-2342) (HRP)

Catalog No. ABIN760400

The Rabbit Polyclonal anti-CASC5 antibody is suitable to detect CASC5 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for CASC5 antibody (AA 2251-2342) (HRP) (ABIN760400)

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC5 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CASC5 Antibody (HRP)

Binding Specificity: AA 2251-2342

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CASC5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CASC5

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Alternative Name: CASC5

Background:

Synonyms: Protein D40/AF15q14, AF15Q14, ALL1 fused gene from chromosome 15q14, Blinkin bub linking kinetochore protein, Cancer susceptibility candidate 5, Cancer susceptibility candidate gene 5 protein, Cancer/testis antigen 29, CT29, D40, hKNL 1, hSpc105, KIAA1570, Kinetochore null 1 homolog, Kinetochore null protein 1, KNL1, CASC5_HUMAN.

Background: Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Four known isoforms exist.

Gene ID: 57082

Pathways: Maintenance of Protein Location, Autophagy