TCF7L1 antibody (C-Term)

Catalog No. ABIN8114129

The Rabbit Polyclonal anti-TCF7L1 antibody is suitable to detect TCF7L1 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Saccharomyces cerevisiae and Sheep. It has been validated for WB.

Quick Overview for TCF7L1 antibody (C-Term) (ABIN8114129)

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Saccharomyces cerevisiae, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF7L1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TCF7L1 Antibody

Binding Specificity: C-Term

Purpose: TCF7L1 Antibody - C-terminal region

Sequence: LHSQLYPTWS ARDNYGKKKK RKREKQLSQT QSQQQVQEAE GALASKSKKP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TF7L1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30091-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCF7L1

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Alternative Name: TCF7L1

Background:

Background Information: This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.

Gene Name: transcription factor 7 like 1

Alternative Symbols: TCF3, TCF-3

Protein Name: transcription factor 7-like 1

Molecular Weight: 64kDa

Gene ID: 83439

NCBI Accession: NP_112573

UniProt: Q9HCS4

Pathways: WNT Signaling, Stem Cell Maintenance