alpha Tubulin antibody (AA 380-420)

Catalog No. ABIN8119670

This Rabbit Polyclonal antibody specifically detects alpha Tubulin in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for alpha Tubulin antibody (AA 380-420) (ABIN8119670)

Target: alpha Tubulin (TUBA1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Tubulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-alpha Tubulin Antibody

Binding Specificity: AA 380-420

Purpose: Tubulin α Antibody

Specificity: The antibody detects endogenous Tubulin α

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 380-420

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for alpha Tubulin

Target: alpha Tubulin (TUBA1)

Alternative Name: Tubulin alpha

Background:

Synonyms: Alpha-tubulin 1 antibody ALS22 antibody B ALPHA 1 antibody bA408E5.3 antibody H2 ALPHA antibody Hum a tub1 antibody Hum a tub2 antibody LIS3 antibody MGC171407 antibody MGC55332 antibody TBA4A_HUMAN antibody Testis-specific alpha-tubulin antibody TUBA1 antibody TUBA1A antibody tuba1l antibody Tuba4a antibody Tubulin alpha 1 chain antibody Tubulin alpha antibody Tubulin alpha-1 chain antibody tubulin alpha-1B chain antibody Tubulin alpha-4A chain antibody Tubulin H2-alpha antibody Tubulin, alpha 1 (testis specific) antibody tubulin, alpha 1, like antibody Tubulin, alpha 4a antibody Tubulin, alpha, testis-specific antibody Tubulin, alpha-1 antibody

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Gene Name: Tubulin alpha

Protein Name: Tubulin alpha

Gene ID: 7846, 10376, 84790

UniProt: Q71U36

Pathways: Microtubule Dynamics