AXL antibody (AA 630-710)

Catalog No. ABIN8119927

The Rabbit Polyclonal anti-AXL antibody (ABIN8119927) specifically detects AXL in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for AXL antibody (AA 630-710) (ABIN8119927)

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AXL Antibody

Binding Specificity: AA 630-710

Purpose: Axl Antibody

Specificity: Axl Polyclonal Antibody detects endogenous levels of Axl protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Axl . at AA range: 630-710

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: Axl

Background:

Synonyms: AXL, UFO, Tyrosine-protein kinase receptor UFO, AXL oncogene

Background: The protein encoded byThis gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],

Gene Name: AXL UFO

Protein Name: Tyrosine-protein kinase receptor UFO

Gene ID: 558

UniProt: P30530

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin