BLK antibody (pTyr389)

Catalog No. ABIN8119933

The Rabbit Polyclonal anti-BLK antibody (ABIN8119933) specifically detects BLK in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BLK antibody (pTyr389) (ABIN8119933)

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BLK Antibody

Binding Specificity: pTyr389

Purpose: BLK (Phospho Tyr389) Antibody

Specificity: This antibody detects endogenous levels of BLK (Phospho-Tyr389) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human BLK (Phospho-Tyr389)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BLK

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Alternative Name: BLK

Background:

Synonyms: Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)

Background: This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],

Gene Name: BLK

Protein Name: BLK (Phospho-Tyr389)

Gene ID: 640

UniProt: P51451

Pathways: Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling