BRD2 antibody (AA 300-350)

Catalog No. ABIN8120042

This Rabbit Polyclonal antibody specifically detects BRD2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BRD2 antibody (AA 300-350) (ABIN8120042)

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BRD2 Antibody

Binding Specificity: AA 300-350

Purpose: BRD2 Antibody

Specificity: BRD2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein AA range: 300-350

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Alternative Name: BRD2

Background:

Background: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010],

Gene Name: BRD2 KIAA9001 RING3

Protein Name: Bromodomain-containing protein 2 (O27.1.1) (Really interesting new gene 3 protein)

Gene ID: 6046

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection