CDC2 / CDK2 antibody (pThr160)

Catalog No. ABIN8120815

The Rabbit Polyclonal anti-CDC2 / CDK2 antibody (ABIN8120815) specifically detects CDC2 / CDK2 in ELISA, WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CDC2 / CDK2 antibody (pThr160) (ABIN8120815)

Target: CDC2 / CDK2 (CDC2) (Cyclin-Dependent Kinase A-1 (CDC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC2 / CDK2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CDC2 / CDK2 Antibody

Binding Specificity: pThr160

Purpose: Cdk2/Cdc2 (phospho Thr160) Antibody

Specificity: Phospho-Cdk2/Cdc2 (T160) Polyclonal Antibody detects endogenous levels of Cdk2/Cdc2 protein only when phosphorylated at T160.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Cdk2/Cdc2 (phospho Thr160)

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CDC2 / CDK2

Target: CDC2 / CDK2 (CDC2) (Cyclin-Dependent Kinase A-1 (CDC2))

Alternative Name: Cdk2/Cdc2

Background:

Synonyms: CDK2, CDKN2, Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase

Background: cyclin dependent kinase 2(CDK2) Homo sapiens This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],

Gene Name: CDK2

Protein Name: Cyclin-dependent kinase 2

Gene ID: 1017

UniProt: P24941