EPH Receptor A2 antibody (pTyr772)

Catalog No. ABIN8121209

This Rabbit Polyclonal antibody specifically detects EPH Receptor A2 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EPH Receptor A2 antibody (pTyr772) (ABIN8121209)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPH Receptor A2 Antibody

Binding Specificity: pTyr772

Purpose: EphA2 (Phospho Tyr772) Antibody

Specificity: This antibody detects endogenous levels of Human EphA2 (phospho-Tyr772)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human EphA2 (Tyr772)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EphA2

Background:

Synonyms: Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010],

Gene Name: EPHA2 ECK

Protein Name: EphA2 (Tyr772)

Gene ID: 1969

UniProt: P29317

Pathways: RTK Signaling