EPH Receptor B4 antibody (pTyr987)

Catalog No. ABIN8121221

This Rabbit Polyclonal antibody specifically detects EPH Receptor B4 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EPH Receptor B4 antibody (pTyr987) (ABIN8121221)

Target: EPH Receptor B4 (EPHB4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPH Receptor B4 Antibody

Binding Specificity: pTyr987

Purpose: EPHB4 (Phospho Tyr987) Antibody

Specificity: This antibody detects endogenous levels of EPHB4 (Phospho-Tyr987) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human EPHB4 (Phospho-Tyr987)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Alternative Name: EPHB4

Background:

Synonyms: Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)

Background: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008],

Gene Name: EPHB4 HTK MYK1 TYRO11

Protein Name: EPHB4 (Phospho-Tyr987)

Gene ID: 2050

UniProt: P54760

Pathways: RTK Signaling