ERBB2IP antibody

Catalog No. ABIN8121256

The Rabbit Polyclonal anti-ERBB2IP antibody (ABIN8121256) specifically detects ERBB2IP in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ERBB2IP antibody (ABIN8121256)

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB2IP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ERBB2IP Antibody

Purpose: Erbin Antibody

Specificity: This antibody detects endogenous levels of Human Erbin Polyclonal Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Erbin

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ERBB2IP

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Alternative Name: Erbin

Background:

Synonyms: Protein LAP2 (Densin-180-like protein, Erbb2-interacting protein, Erbin)

Background: This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Gene Name: ERBB2IP ERBIN KIAA1225 LAP2

Protein Name: Erbin Polyclonal Antibody

Gene ID: 55914

UniProt: Q96RT1

Pathways: EGFR Signaling Pathway, Asymmetric Protein Localization