FANCG antibody (pSer383)

Catalog No. ABIN8121380

This Rabbit Polyclonal antibody specifically detects FANCG in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FANCG antibody (pSer383) (ABIN8121380)

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FANCG Antibody

Binding Specificity: pSer383

Purpose: FANCG (phospho Ser383) Antibody

Specificity: Phospho-FANCG (S383) Polyclonal Antibody detects endogenous levels of FANCG protein only when phosphorylated at S383.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human FANCG (phospho Ser383)

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG

Background:

Synonyms: FANCG, XRCC9, Fanconi anemia group G protein, Protein FACG, DNA repair protein XRCC9

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008],

Gene Name: FANCG

Protein Name: Fanconi anemia group G protein

Gene ID: 2189

UniProt: O15287

Pathways: DNA Damage Repair