GSDMD antibody (AA 400-500)

Catalog No. ABIN8121603

The Mouse Monoclonal anti-GSDMD antibody is suitable to detect GSDMD in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for GSDMD antibody (AA 400-500) (ABIN8121603)

Target: GSDMD (Gasdermin D (GSDMD))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This GSDMD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: AB2424

Product Details anti-GSDMD Antibody

Binding Specificity: AA 400-500

Purpose: GSDMD mouse mAb

Specificity: This antibody detects endogenous levels of GSDMD protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 400 - 500 of the human Beta Tubulin protein.

Isotype: IgG

Application Details

Application Notes: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for GSDMD

Target: GSDMD (Gasdermin D (GSDMD))

Alternative Name: GSDMD

Background:

Synonyms: Gasdermin-D (Gasdermin domain-containing protein 1)

Background: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Gene Name: GSDMD

Protein Name: GSDMD

Gene ID: 79792

UniProt: P57764

Pathways: Inflammasome