Glutaminase antibody (AA 162-212)

Catalog No. ABIN8121696

The Rabbit Polyclonal anti-Glutaminase antibody is suitable to detect Glutaminase in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Glutaminase antibody (AA 162-212) (ABIN8121696)

Target: Glutaminase (GLS)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaminase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutaminase Antibody

Binding Specificity: AA 162-212

Purpose: GLSK Antibody

Specificity: This antibody detects endogenous levels of GLSK at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GLSK AA range: 162-212

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Glutaminase

Target: Glutaminase (GLS)

Alternative Name: GLSK

Background:

Background: This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],

Gene Name: GLS GLS1 KIAA0838

Protein Name: GLSK

Gene ID: 2744

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effect