H2AFZ antibody (AA 1-30)

Catalog No. ABIN8121867

The Rabbit Polyclonal anti-H2AFZ antibody is suitable to detect H2AFZ in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for H2AFZ antibody (AA 1-30) (ABIN8121867)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-H2AFZ Antibody

Binding Specificity: AA 1-30

Purpose: Histone H2A.Z Antibody

Specificity: The antibody detects endogenous Histone H2A.Z

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 1-30

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: Histone H2A.Z

Background:

Synonyms: Histone H2A.Z (H2A/z)

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],

Gene Name: H2AFZ H2AZ

Protein Name: Histone H2A.Z (H2A/z)

Gene ID: 3015

UniProt: P0C0S5

Pathways: Telomere Maintenance