HNF1A antibody (pSer247)

Catalog No. ABIN8122096

The Rabbit Polyclonal anti-HNF1A antibody (ABIN8122096) specifically detects HNF1A in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HNF1A antibody (pSer247) (ABIN8122096)

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HNF1A Antibody

Binding Specificity: pSer247

Purpose: HNF1α (Phospho Ser247) Antibody

Specificity: This antibody detects endogenous levels of Human HNF1α (phospho-Ser247)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human HNF1alpha (Ser247)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Alternative Name: HNF1alpha

Background:

Synonyms: Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1)

Background: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

Gene Name: HNF1A TCF1

Protein Name: HNF1α (Ser247)

Gene ID: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis