INSIG2 antibody (AA 40-120)

Catalog No. ABIN8122221

The Rabbit Polyclonal anti-INSIG2 antibody is suitable to detect INSIG2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for INSIG2 antibody (AA 40-120) (ABIN8122221)

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSIG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-INSIG2 Antibody

Binding Specificity: AA 40-120

Purpose: INSI2 Antibody

Specificity: INSI2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for INSIG2

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Alternative Name: INSI2

Background:

Background: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq, Jul 2008],

Gene Name: INSIG2

Protein Name: Insulin-induced gene 2 protein (INSIG-2)

Gene ID: 51141

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling