IRF5 antibody (pSer437)

Catalog No. ABIN8122295

This Rabbit Polyclonal antibody specifically detects IRF5 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IRF5 antibody (pSer437) (ABIN8122295)

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRF5 Antibody

Binding Specificity: pSer437

Purpose: IRF5 (Phospho Ser437) Antibody

Specificity: This antibody detects endogenous levels of IRF5 (Phospho-Ser437) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human IRF5 (Phospho-Ser437)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IRF5

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Alternative Name: IRF5

Background:

Synonyms: Interferon regulatory factor 5 (IRF-5)

Background: This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010],

Gene Name: IRF5

Protein Name: IRF5 (Phospho-Ser437)

Gene ID: 3663

UniProt: Q13568

Pathways: TLR Signaling, Autophagy