LEPREL1 antibody

Catalog No. ABIN8122620

The Rabbit Polyclonal anti-LEPREL1 antibody is suitable to detect LEPREL1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for LEPREL1 antibody (ABIN8122620)

Target: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEPREL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LEPREL1 Antibody

Purpose: P3H2 Antibody

Specificity: P3H2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LEPREL1

Target: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Alternative Name: P3H2

Background:

Background: This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Gene Name: LEPREL1 MLAT4 P3H2

Protein Name: Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4)

Gene ID: 55214

UniProt: Q8IVL5