MAP3K2 antibody (pSer520)

Catalog No. ABIN8123018

This Rabbit Polyclonal antibody specifically detects MAP3K2 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MAP3K2 antibody (pSer520) (ABIN8123018)

Target: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP3K2 Antibody

Binding Specificity: pSer520

Purpose: MAP3K2 (Phospho Ser520) Antibody

Specificity: This antibody detects endogenous levels of MAP3K2 (Phospho-Ser520) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human MAP3K2 (Phospho-Ser520)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MAP3K2

Target: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Alternative Name: MAP3K2

Background:

Synonyms: Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)

Background: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008],

Gene Name: MAP3K2 MAPKKK2 MEKK2

Protein Name: MAP3K2 (Phospho-Ser520)

Gene ID: 10746

UniProt: Q9Y2U5

Pathways: MAPK Signaling