MPRIP antibody (pSer227)

Catalog No. ABIN8123152

The Rabbit Polyclonal anti-MPRIP antibody (ABIN8123152) specifically detects MPRIP in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for MPRIP antibody (pSer227) (ABIN8123152)

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPRIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-MPRIP Antibody

Binding Specificity: pSer227

Purpose: RIP3 (Phospho Ser227) Antibody

Specificity: This antibody detects endogenous levels of Human RIP3 (phospho-Ser227)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human RIP3 (Ser227)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MPRIP

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Alternative Name: RIP3

Background:

Synonyms: Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)

Background: The product ofThis gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],

Gene Name: RIPK3 RIP3

Protein Name: RIP3 (Ser227)

Gene ID: 11035

UniProt: Q9Y572