Paired Box 3 antibody (AA 150-230)

Catalog No. ABIN8123563

The Rabbit Polyclonal anti-Paired Box 3 antibody (ABIN8123563) specifically detects Paired Box 3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Paired Box 3 antibody (AA 150-230) (ABIN8123563)

Target: Paired Box 3 (PAX3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paired Box 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Paired Box 3 Antibody

Binding Specificity: AA 150-230

Purpose: PAX3 Antibody

Specificity: PAX3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 150-230

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3

Background:

Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008],

Gene Name: PAX3 HUP2

Protein Name: Paired box protein Pax-3 (HuP2)

Gene ID: 5077

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation