PSPC1 antibody (AA 10-90)

Catalog No. ABIN8123596

The Rabbit Polyclonal anti-PSPC1 antibody (ABIN8123596) specifically detects PSPC1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PSPC1 antibody (AA 10-90) (ABIN8123596)

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSPC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PSPC1 Antibody

Binding Specificity: AA 10-90

Purpose: PSPC1 Antibody

Specificity: PSPC1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PSPC1

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Alternative Name: PSPC1

Background:

Background: This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism.The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified. [provided by

Gene Name: PSPC1 PSP1

Protein Name: Paraspeckle component 1 (Paraspeckle protein 1)

Gene ID: 55269

UniProt: Q8WXF1