Perforin 1 antibody (AA 1-100)

Catalog No. ABIN8123650

The Mouse Monoclonal anti-Perforin 1 antibody (Clone AB1420) (ABIN8123650) specifically detects Perforin 1 in WB, IHC, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for Perforin 1 antibody (AA 1-100) (ABIN8123650)

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Perforin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB1420

Product Details anti-Perforin 1 Antibody

Binding Specificity: AA 1-100

Purpose: Perforin mouse mAb

Specificity: The antibody can specifically recognize human Perforin protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human Perforin protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:100-1:500 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Perforin 1

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Alternative Name: Perforin

Background:

Synonyms: Cytolysin, FLH2, HPLH2, Lymphocyte pore-forming protein, P1, PERF_HUMAN, perforin 1 (pore forming protein) , Perforin 1, Perforin-1, PFP, PGFL, PIGF, PIGF-2, PLGF, Pore forming protein, prf1, SHGC-10760

Background: Perforin is a specific marker of activated cytotoxic T cells and natural killer cells. It can destroy the corresponding target cell membrane and induce apoptosis. It is mainly expressed in CD3 negative and CD56 positive NK cells, CD3 positive large granular lymphocytes and γδ Type T cells. It is mainly used for the auxiliary diagnosis of NK cell lymphoma and NK cell like T-cell lymphoma.

Gene Name: PRF1 PFP

Protein Name: Perforin

Gene ID: 5551

UniProt: P14222

Pathways: Apoptosis, Caspase Cascade in Apoptosis