PCNT antibody

Catalog No. ABIN8123651

This Rabbit Polyclonal antibody specifically detects PCNT in IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for PCNT antibody (ABIN8123651)

Target: PCNT (Pericentrin (PCNT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCNT antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PCNT Antibody

Purpose: PCNT Antibody

Specificity: PCNT Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: IHC 1:50-300. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PCNT

Target: PCNT (Pericentrin (PCNT))

Alternative Name: PCNT

Background:

Background: The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

Gene Name: PCNT KIAA0402 PCNT2

Protein Name: Pericentrin (Kendrin) (Pericentrin-B)

Gene ID: 5116

UniProt: O95613

Pathways: Sensory Perception of Sound, M Phase, SARS-CoV-2 Protein Interactome