Peroxiredoxin 1 antibody (pTyr194)

Catalog No. ABIN8123663

This Rabbit Polyclonal antibody specifically detects Peroxiredoxin 1 in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Peroxiredoxin 1 antibody (pTyr194) (ABIN8123663)

Target: Peroxiredoxin 1 (PRDX1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Peroxiredoxin 1 Antibody

Binding Specificity: pTyr194

Purpose: Prdx1 (Phospho Tyr194) Antibody

Specificity: This antibody detects endogenous levels of Human Prdx1 (phospho-Tyr194)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Prdx1 (Tyr194)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Alternative Name: Prdx1

Background:

Synonyms: Peroxiredoxin-1 (EC 1.11.1.15) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2)

Background: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011],

Gene Name: PRDX1 PAGA PAGB TDPX2

Protein Name: Prdx1 (Tyr194) ,Peroxiredoxin-1

Gene ID: 5052

UniProt: Q06830

Pathways: p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events