PRSS2 antibody

Catalog No. ABIN8124020

This Rabbit Polyclonal antibody specifically detects PRSS2 in WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PRSS2 antibody (ABIN8124020)

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PRSS2 Antibody

Purpose: TRY2 Antibody

Specificity: This antibody detects endogenous levels of human TRY2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human TRY2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PRSS2

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Alternative Name: TRY2

Background:

Synonyms: Trypsin-2 (EC 3.4.21.4, Anionic trypsinogen, Serine protease 2, Trypsin II)

Background: This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015],

Gene Name: PRSS2 TRY2 TRYP2

Protein Name: TRY2

Gene ID: 5645

UniProt: P07478