PPP1R13B antibody (AA 630-680)

Catalog No. ABIN8124096

The Rabbit Polyclonal anti-PPP1R13B antibody is suitable to detect PPP1R13B in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for PPP1R13B antibody (AA 630-680) (ABIN8124096)

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R13B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PPP1R13B Antibody

Binding Specificity: AA 630-680

Purpose: ASPP1 Antibody

Specificity: The antibody detects endogenous ASPP1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 630-680

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PPP1R13B

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Alternative Name: ASPP1

Background:

Synonyms: Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)

Background: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008],

Gene Name: PPP1R13B ASPP1 KIAA0771

Protein Name: Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)

Gene ID: 23368

UniProt: Q96KQ4

Pathways: p53 Signaling