RIN2 antibody (AA 70-150)

Catalog No. ABIN8124238

The Rabbit Polyclonal anti-RIN2 antibody (ABIN8124238) specifically detects RIN2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for RIN2 antibody (AA 70-150) (ABIN8124238)

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RIN2 Antibody

Binding Specificity: AA 70-150

Purpose: RIN2 Antibody

Specificity: RIN2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RIN2

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Alternative Name: RIN2

Background:

Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway.The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],

Gene Name: RIN2 RASSF4

Protein Name: Ras and Rab interactor 2 (Ras association domain family 4) (Ras inhibitor JC265) (Ras interaction/interference protein 2)

Gene ID: 54453

UniProt: Q8WYP3