Septin 5 antibody (AA 180-260)

Catalog No. ABIN8124586

The Rabbit Polyclonal anti-Septin 5 antibody (ABIN8124586) specifically detects Septin 5 in WB and IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Septin 5 antibody (AA 180-260) (ABIN8124586)

Target: Septin 5 (SEPT5)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Septin 5 Antibody

Binding Specificity: AA 180-260

Purpose: Septin 5 Antibody

Specificity: Septin 5 Polyclonal Antibody detects endogenous levels of Septin 5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Septin 5 . at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Septin 5

Target: Septin 5 (SEPT5)

Alternative Name: Septin 5

Background:

Synonyms: SEPT5, PNUTL1, Septin-5, Cell division control-related protein 1, CDCrel-1, Peanut-like protein 1

Background: septin 5(SEPT5) Homo sapiens This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010],

Gene Name: SEPT5

Protein Name: Septin-5

Gene ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis