SAA1 antibody (AA 38-88)

Catalog No. ABIN8124630

The Rabbit Polyclonal anti-SAA1 antibody is suitable to detect SAA1 in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for SAA1 antibody (AA 38-88) (ABIN8124630)

Target: SAA1 (Serum Amyloid A1 (SAA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SAA1 Antibody

Binding Specificity: AA 38-88

Purpose: SAA1 Antibody

Specificity: SAA1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein AA range: 38-88

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Alternative Name: SAA1

Background:

Background: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Feb 2016],

Gene Name: SAA1

Protein Name: Serum amyloid A-1 protein (SAA) [Cleaved into: Amyloid protein A (Amyloid fibril protein AA)Serum amyloid protein A(2-104)Serum amyloid protein A(3-104)Serum amyloid protein A(2-103)Serum amyloid protein A(2-102)Serum amyloid protein A(4-101)]

Gene ID: 6288

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades