SRP72 antibody

Catalog No. ABIN8124681

The Rabbit Monoclonal anti-SRP72 antibody is suitable to detect SRP72 in samples from Human. It has been validated for WB, IHC, FACS, ICC and IF.

Quick Overview for SRP72 antibody (ABIN8124681)

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SRP72 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AB2259

Product Details anti-SRP72 Antibody

Purpose: SRP72 Rabbit mAb

Specificity: This antibody detects endogenous levels of SRP72 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:100-1:300 | IF, 1:100-1:300 | FC, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. |

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for SRP72

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Alternative Name: SRP72

Background:

Synonyms: SRP72, Signal recognition particle subunit SRP72 , SRP72, Signal recognition particle 72 kDa protein,

Background: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP) , a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER) . The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

Gene Name: SRP72

Protein Name: SRP72

Gene ID: 6731

UniProt: O76094

Pathways: SARS-CoV-2 Protein Interactome