SSRP1 antibody (AA 209-259)

Catalog No. ABIN8125000

The Rabbit Polyclonal anti-SSRP1 antibody (ABIN8125000) specifically detects SSRP1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SSRP1 antibody (AA 209-259) (ABIN8125000)

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSRP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SSRP1 Antibody

Binding Specificity: AA 209-259

Purpose: SSRP1 Antibody

Specificity: This antibody detects endogenous levels of SSRP1 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human SSRP1 AA range: 209-259

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SSRP1

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Alternative Name: SSRP1

Background:

Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008],

Gene Name: SSRP1 FACT80

Protein Name: SSRP1

Gene ID: 6749

UniProt: Q08945

Pathways: Chromatin Binding