NFE4 antibody (acLys43)

Catalog No. ABIN8125281

The Rabbit Polyclonal anti-NFE4 antibody is suitable to detect NFE4 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for NFE4 antibody (acLys43) (ABIN8125281)

Target: NFE4 (Transcription Factor NF-E4 (NFE4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NFE4 Antibody

Binding Specificity: acLys43

Purpose: NF-E4 (Acetyl Lys43) Antibody

Specificity: Acetyl-NF-E4 (K43) Polyclonal AntibodySynthesized peptide derived from the human NF-E4 around the acetylation site of K43.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NFE4

Target: NFE4 (Transcription Factor NF-E4 (NFE4))

Alternative Name: NF-E4

Background:

Synonyms: NFE4, Transcription factor NF-E4

Background: The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],

Gene Name: NFE4

Protein Name: Transcription factor NF-E4

Gene ID: 58160

UniProt: Q86UQ8