NFE4 antibody

Catalog No. ABIN8125282

The Rabbit Polyclonal anti-NFE4 antibody (ABIN8125282) specifically detects NFE4 in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NFE4 antibody (ABIN8125282)

Target: NFE4 (Transcription Factor NF-E4 (NFE4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NFE4 Antibody

Purpose: NF-E4 Antibody

Specificity: This antibody detects endogenous levels of human NF-E4

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human NF-E4

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NFE4

Target: NFE4 (Transcription Factor NF-E4 (NFE4))

Alternative Name: NF-E4

Background:

Synonyms: Transcription factor NF-E4

Background: The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],

Gene Name: NFE4

Protein Name: NF-E4

Gene ID: 58160

UniProt: Q86UQ8