Transportin 1 antibody

Catalog No. ABIN8125369

The Rabbit Polyclonal anti-Transportin 1 antibody (ABIN8125369) specifically detects Transportin 1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Transportin 1 antibody (ABIN8125369)

Target: Transportin 1 (TNPO1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transportin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Transportin 1 Antibody

Purpose: TNPO1 Antibody

Specificity: TNPO1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Transportin 1

Target: Transportin 1 (TNPO1)

Alternative Name: TNPO1

Background:

Background: This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. [provided by RefSeq, Jul 2008],

Gene Name: TNPO1 KPNB2 MIP1 TRN

Protein Name: Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP)

Gene ID: 3842

UniProt: Q92973

Pathways: PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events