TSEN2 antibody

Catalog No. ABIN8125405

The Rabbit Polyclonal anti-TSEN2 antibody (ABIN8125405) specifically detects TSEN2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TSEN2 antibody (ABIN8125405)

Target: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSEN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TSEN2 Antibody

Purpose: SEN2 Antibody

Specificity: SEN2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TSEN2

Target: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Alternative Name: SEN2

Background:

Background: This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2009],

Gene Name: TSEN2 SEN2

Protein Name: tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2) (HsSen2)

Gene ID: 80746

UniProt: Q8NCE0

Pathways: Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha